fosphenytoin


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Related to fosphenytoin: Fosphenytoin sodium

fosphenytoin

 [fos´fen-ĭ-toin″]
a prodrug of phenytoin used as the sodium salt in treatment of epilepsy, excluding the petit mal type; administered intravenously or intramuscularly.

fosphenytoin

(fŏs′fĕn′ĭ-tō′ĭn, -fə-nĭt′ō-)
n.
A prodrug that is metabolized to phenytoin and administered parenterally for the treatment of seizures.

fosphenytoin

Cerebyx® Neurology A prodrug of phenytoin, which is pharmacologically equivalent to, but causes less phlebitis, soft tissue damage. See Phenytoin, Seizure. Cf Status spilepticus.
References in periodicals archive ?
For the 12 months ending 31 October 2016, the Fosphenytoin Sodium Injection USP, 75 mg/ml, (50 mg PE/ml), packaged in 100 mg PE/2 ml, and 500 mg PE/10 ml single-use vials had US sales of approximately USD36.3m, according to IMS Health.
Until the FDA completes the evaluation, "health care providers should consider avoiding phenytoin and fosphenytoin as alternatives for carbamazepine in patients who test positive for HLA-B*1502."
However, because the potential risks associated with phenytoin and fosphenytoin still are being investigated, "there is not yet enough information to recommend testing" for the allele in patients of Asian ancestry being considered for treatment with one of these two antiepileptic drugs.
Fosphenytoin was created to overcome some of the limitations of phenytoin.
Newer antiepileptic drugs: gabapentin, lamotrigine, felbamate, topiramate and fosphenytoin. American Family Physician.
These medications include phenobarbital, primidone (Mysoline), phenytoin (Dilantin), carbamazepine (Tegretol), fosphenytoin (Cerebyx), and valproic acid (Depakote).
ampicillin (Polycillin) ciprofloxacin (Cipro) Anticonvulsants: Act on the central nervous ethosuximide (Zarontin) system to reduce number fosphenytoin (Cerebyx) and severity of seizures.
Fosphenytoin (1) and mycophenolate mofetil (MMF) (2) are two examples of prodrugs where monitoring of the active drug, the anticonvulsant phenytoin and the immunosuppressant mycophenolic acid (MPA), respectively, is used to guide therapy.
New antiepileptics approved in the 1990s include felbamate, gabapentin, lamotrigine, topiramate, tiagabine, and fosphenytoin (Pellock, 1996).
She was treated acutely with lorazepam and loaded on both Keppra and fosphenytoin, and her seizures stopped.
NEW YORK -- Amneal Biosciences, a unit of Amneal Pharmaceuticals LLC, has launched its first product: generic fosphenytoin sodium injection.